No, it is not possible to run MetaDefender Kiosk using a limited-privilege account. A core functionality of MetaDefender Kiosk requires admin access to the host OS and this is not expected to change in the future versions.
To preserve the integrity of your Kiosk environment, you are encouraged to follow the steps outlined in the MetaDefender Kiosk Documentation.
This article pertains to MetaDefender Kiosk
This article was last updated on 2018-03-27